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Fig. 5 | EJNMMI Research

Fig. 5

From: Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

Fig. 5

uPAR in inflammatory bowel disease. a Macrophage uPAR D1-D3 expression plays a significant role in the bacterial removal while (b) in inflammatory bowel disease macrophage differentiation is altered with as consequence an increase in uPAR D2-D3 expression and inadequate microbial maintenance. uPAR is represented by the red 3-domain structure as described in Fig. 1 on the cell membrane of uPAR expressing cells

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