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EJNMMI Research
Fig. 6 | EJNMMI Research

Fig. 6

From: 18F-FDG PET and DCE kinetic modeling and their correlations in primary NSCLC: first voxel-wise correlative analysis of human simultaneous [18F]FDG PET-MRI data

Fig. 6

Regional decoupling between perfusion/vascularization and metabolism. In all these tumors, whereas MRGlu appears relatively homogeneous, deep central hypoperfused/vascularized areas of variable sizes are visible (low Ktrans, vp, or vb), mirrored by high metabolic enzymatic activity (k3). This pattern is highly suggestive of hypoxic tumor areas, a well-known hallmark of cancer aggressiveness

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