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Table 3 Organ residence times (hours) of 11C-UCB-J in humans in comparison with those in non-human primate (NHP). All values displayed as mean ± standard deviation

From: Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

Organ Mean ALL human (n = 4) Mean ALL NHP (n = 4) Percent difference (%)
Brain 0.0733 ± 0.0161 0.0729 ± 0.0045 − 1
Gallbladder 0.0033 ± 0.0012 0.0004 ± 0.0002 − 88
Heart 0.0057 ± 0.0009 0.0033 ± 0.0013 − 42
Lower intestine 0.0216 ± 0.0051 0.0073 ± 0.0020 − 66
Kidneys 0.0091 ± 0.0008 0.0122 ± 0.0023 34
Liver 0.0956 ± 0.0148 0.0965 ± 0.0407 1
Lungs 0.0134 ± 0.0063 0.0127 ± 0.0061 − 5
Pancreas 0.0003 ± 0.0001 0.0001 ± 0.0001 − 66
Spleen 0.0020 ± 0.0002 0.0018 ± 0.0005 − 10
Stomach 0.0079 ± 0.0067 0.0007 ± 0.0002 − 91
Urinary bladder 0.0259 ± 0.0010 0.0072 ± 0.0039 − 72
Remainder 0.2302 ± 0.0313 0.2730 ± 0.0455 19