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Table 3 Organ residence times (hours) of 11C-UCB-J in humans in comparison with those in non-human primate (NHP). All values displayed as mean ± standard deviation

From: Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

Organ

Mean ALL human (n = 4)

Mean ALL NHP (n = 4)

Percent difference (%)

Brain

0.0733 ± 0.0161

0.0729 ± 0.0045

− 1

Gallbladder

0.0033 ± 0.0012

0.0004 ± 0.0002

− 88

Heart

0.0057 ± 0.0009

0.0033 ± 0.0013

− 42

Lower intestine

0.0216 ± 0.0051

0.0073 ± 0.0020

− 66

Kidneys

0.0091 ± 0.0008

0.0122 ± 0.0023

34

Liver

0.0956 ± 0.0148

0.0965 ± 0.0407

1

Lungs

0.0134 ± 0.0063

0.0127 ± 0.0061

− 5

Pancreas

0.0003 ± 0.0001

0.0001 ± 0.0001

− 66

Spleen

0.0020 ± 0.0002

0.0018 ± 0.0005

− 10

Stomach

0.0079 ± 0.0067

0.0007 ± 0.0002

− 91

Urinary bladder

0.0259 ± 0.0010

0.0072 ± 0.0039

− 72

Remainder

0.2302 ± 0.0313

0.2730 ± 0.0455

19