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Fig. 7 | EJNMMI Research

Fig. 7

From: Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis

Fig. 7

Mitochondrial ultrastructure and bioenergetics activity in cardiac myocardium of SOD1G93A and control mice. a, b Electron microscopy representative images of control SOD1G93A myocardium. c, d ATP synthesis and oxygen consumption rate stimulated by pyruvate/malate in control (green column) and SOD1G93A (red column) of isolated mitochondria. e Complex I activity in isolated mitochondria of control (green column) and of mutated muscles (red column) studied by the FeCN reduction in the presence of NADH. Data are expressed as mean ± SD, n = 3 for each group. Student t test for unpaired data was used for statistical evaluation

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