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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis

Fig. 4

Antioxidant response and oxidative stress in SOD1G93A mutation. a, b NADPH levels and total NADP+NADPH content in control (green column) and SOD1G93A (red column) quadricep homogenates represented as percent of control. c GR activity and d MDA content in control (green column) and SOD1G93A (red column) quadriceps. e Mean fluorescence index (MFI) of H2DCFDA in control and SOD1G93A quadriceps muscles. f Immunofluorescence representative images of MitoTracker® (as specific mitochondria staining—red fluorescence), H2DCFDA (as specific ROS staining—green fluorescence), and colocalization staining signals, in control and SOD1G93A quadriceps. Data are expressed as mean ± SD, n = 3 for each group. Student t test for unpaired data was used for statistical evaluation

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