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Fig. 1 | EJNMMI Research

Fig. 1

From: Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis

Fig. 1

In vivo and ex vivo effects of SOD1G93A mutation in skeletal muscle. a, b Bodyweight and serum glucose levels in controls (green column) and SOD1G93A mice (red column). c Average of FDG retention expressed as standardized uptake value ratio (SUVr) in control (green column) and SOD1G93A skeletal muscle (red column). d Representative hindlimb SUV of control and SOD1G93A mice. e Average time-course of “ex-vivo” radioactivity expressed as a fraction of the FDG dose measured by the Ligand-Tracer White® device, in quadriceps harvested from control (green line) and SOD1G93A mouse (red line). f Ex vivo glucose consumption of harvested quadriceps from control (green column) and SOD1G93A mouse (red column). Data are expressed as mean ± SD; adn = 5 for each group; e, fn = 3 for each group. Student t test for unpaired data was used for statistical evaluation

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