Table 1 MRI protocol parameters for cohorts 1 and 2

Description

3D volumetric

3D volumetric

Interpolated two point

Interpolated multi-echo

Gradient-echo sequence

Gradient-echo sequence

Echo times (ms)

TE1 = 1.1 (out-of-phase), TE2 = 2.2 (in-phase)

TE1 = 1.09, TE2 = 3.19, TE3 = 5.29, TE4 = 7.39, TE5 = 9.49, TE6 = 11.59

Repetition time (ms)

4

13.5

Flip angle (°)

5

6

Field of view (mm)

500 × 500

256 (read) × 384 (phase)

Image size (voxels)

256 × 256 × 256

192 × 288 × 72

Voxel size (mm)

2.0 × 2.0 × 2.6

1.3 × 1.3 × 1.3

Slice thickness (mm)

2.6

1.3

Field of view phase direction (%)

75

150

Pixel bandwidth (Hz/Px)

1302

810

Slices per slab

120 (per bed position)

72

Acquisition time (min)

0:18 (per bed position)

6:26