Table 1 Correspondence between kinfitr and PMOD
Pearson’s r | ICC | Bias (%) | |||||
|---|---|---|---|---|---|---|---|
Ligand | Model | Region 1 | Region 2 | Region 1 | Region 2 | Bias 1 | Bias 2 |
Invasive | |||||||
[11C]PBR28 | 2TCM | 1.00 | 1.00 | 0.99 | 1.00 | 2.01 | 1.19 |
Logan | 1.00 | 1.00 | 0.99 | 0.99 | 0.47 | − 0.27 | |
MA1 | 1.00 | 0.99 | 0.95 | 0.97 | 10.07 | 9.55 | |
[11C]PK11195 | 2TCM | 1.00 | 0.98 | 1.00 | 0.98 | 1.16 | 0.69 |
Logan | 1.00 | 0.97 | 0.99 | 0.94 | − 3.40 | − 5.88 | |
MA1 | 0.99 | 0.95 | 0.97 | 0.89 | 4.99 | 9.54 | |
Non-invasive | |||||||
[11C]AZ10419369 | SRTM | 1.00 | 1.00 | 1.00 | 1.00 | -0.17 | 0.13 |
ref Logan | 0.99 | 0.99 | 0.93 | 0.91 | − 2.95 | − 3.55 | |
MRTM2 | 0.97 | 0.96 | 0.86 | 0.80 | − 3.94 | − 5.35 | |
[11C]SCH23390 | SRTM | 1.00 | 1.00 | 1.00 | 1.00 | 0.24 | 0.53 |
ref Logan | 0.99 | 0.99 | 0.88 | 0.96 | − 5.26 | − 4.31 | |
MRTM2 | 1.00 | 1.00 | 0.98 | 0.99 | − 2.07 | − 2.17 | |