Skip to main content
Fig. 4 | EJNMMI Research

Fig. 4

From: Selective serotonin reuptake inhibitors (SSRIs) prevent meta-iodobenzylguanidine (MIBG) uptake in platelets without affecting neuroblastoma tumor uptake

Fig. 4

Inhibition of [3H]serotonin and [125I]MIBG uptake by SSRIs in human platelets. Inhibition of [3H]serotonin uptake is depicted by open symbols (), and inhibition of [125I]MIBG uptake by closed symbols (■). Samples were incubated at 37 °C for 15 min (serotonin) or 4 h (MIBG) with a substrate concentration of 10−8 M. Substrate uptake is expressed as the percentage of control without inhibitor. Data represent mean ± SD (n = 4–7)

Back to article page