Combined PET/CT with thoracic contrast-enhanced CT in assessment of primary cardiac tumors in adult patients

EJNMMI Research

Table 1 Characteristics of patients (n = 46)

	All	Benign tumors	Malignant tumors	P value
Number of patients	46	29	17
Age (years)	44.8 (15.0–71.0)	45.4 (15.0–71.0)	43.7 (20.0–63.0)	0.711
Gender, n (%)				0.885
Male	25	16	9
Female	21	13	8
Blood glucose level (mmol/l)	5.4	5.2	5.6	0.062
¹⁸F-FDG injected dose (MBq)	409.8	407.1	414.4	0.792
Size (cm)
Length	4.2 (0.8–16.9)	3.4 (0.8–8.4)	5.2 (1.8–16.9)	0.006
Width	3.5 (1.1–10.0)	3.4 (1.1–7.9)	4.2 (1.9–10.0)	0.085
Height	3.9 (0.7–14.4)	3.5 (0.7–8.1)	6.9 (3.3–14.4)	0.003
Location				0.923
Atrium	30	18	12
Left	10	7	3
Right	20	11	9
Ventricle	16	11	5
Left	4	3	1
Right	12	8	4
Calcification	6	5	1
ΔHU	20.5 (1.0–76.0)	17.0 (1.0–65.0)	26.0 (18.0–76.0)	< 0.001
SUVmax_background	2.1 (1.3–3.0)	2.1 (1.3–2.9)	2.2 (1.8–3.0)	0.471
SUVmax_tumor	3.5 (0.8–20.4)	2.7 (0.8–4.9)	6.7 (3.5–20.4)	< 0.001
SUVmean_tumor	2.4 (0.6–8.6)	2.0 (0.6–4.6)	4.3 (2.2–8.6)	< 0.001
SUVmax_Glu_corrected	3.4 (0.7–22.8)	2.5 (0.7–5.7)	6.6 (3.4–22.8)	< 0.001
TBR	1.7 (0.5–11.3)	1.3 (0.5–2.3)	3.2 (1.3–11.3)	< 0.001
Pleural effusion	13	3	10	< 0.001
Pericardial effusion	16	3	13	< 0.001
Treatment and histopathology
Complete resection	35	28	7
Partial resection	4		4
Biopsy only	5		5
No histopathology	2	1^*	1^†
Newly diagnosed	42	26	16
Recurrences	4	3	1
Tumor classification, n (%)
Benign tumors		29
Myxoma		19
Hemangioma		4
Lipoma		3
Other		3
Malignant tumors			17
Sarcoma			12
Angiosarcoma			6
Leiomyosarcoma			2
Other			4
Lymphoma			2
Intermediate Malignant tumors^‡			2
Other			1
Metastasis
Thoracic metastasis			5
Distant metastasis			1^§

^*One case of lipoma diagnosed by CT, without histopathology
^†Recurrence of right ventricular myxoid malignant fibrous histiocytoma 1 year after resection, had no operation and no pathology
^‡Including two cases of intermediate tumors (including 1 Kaposiform hemangioendothelioma and 1 fibrous tumor)
^§Simultaneous intrathoracic and distant metastases in the one patient