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Fig. 4 | EJNMMI Research

Fig. 4

From: A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts

Fig. 4

Sequential 4FMFES and 89Zr-T PET imaging in an orthotopic MCF-7 or JIMT-1 mouse model. a Representative coronal slices of 4FMFES-injected mice bearing either MCF-7 at 45 min p.i. or JIMT-1 tumors (white arrows). b 4FMFES PET-derived uptake reported in %IA/g of relevant organs and tumor-to-muscle ratios for each tumor type. c Representative coronal slices of 89Zr-T at 144 h p.i. of MCF-7 or JIMT-1 tumor-bearing mice (white arrows). d89Zr-T PET-derived uptake of relevant organs in %IA/g and tumor-to-muscle ratios for each tumor type. *p < 0.05; ***p < 0.005; ****p < 0.001

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