Fig. 7

PD-L1-specific CLI at different time points in human CRC xenograft models with ¹³¹I-labeled PD-L1 antibody. a Cerenkov images of nude mice bearing four different CRC cell lines at 24 h, 48 h, and 120 h. b After injection of ¹³¹I-PD-L1-Mab (37 MBq), the areas of interest were delineated along the tumor margin at 24 h, 48 h, and 120 h to quantitatively measure the Cerenkov fluorescence intensity of the tumor-to-background ratio. c The diagnostic effectiveness of Cerenkov images was tested by receiver operating characteristic curves. The data are expressed as means ± SD, *** p < 0.001