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Table 2 Overview of ROC analyses for 68Ga-RM2-PET and 68Ga-PSMA-11-PET with binary histoPET as reference

From: Voxel-based comparison of [68Ga]Ga-RM2-PET/CT and [68Ga]Ga-PSMA-11-PET/CT with histopathology for diagnosis of primary prostate cancer

Patient No.AUC RM2[68Ga]Ga-RM2 SUV threshold for a sensitivity ≥ 0.9 [g/ml]Relative threshold for [68Ga]Ga-RM2 (SUV/SUVmax)Corresponding specificity (RM2)AUC PSMABest absolute PSMA SUV threshold for a sensitivity ≥ 0.9 [g/ml]1Relative threshold for PSMA (SUV/SUVmax)1Corresponding specificity (PSMA)1
10.801.910.140.620.761.580.240.48
20.841.380.310.630.861.680.210.55
30.711.120.240.340.8911.490.210.72
40.691.610.090.180.561.190.210.31
50.722.140.320.460.801.370.360.52
60.852.980.300.640.835.350.340.79
70.933.350.290.870.951.930.460.81
80.891.950.380.680.892.010.290.67
Mean0.80 ± 0.102.06 ± 0.770.25 ± 0.110.55 ± 0.200.82 ± 0.123.32 ± 3.560.29 ± 0.090.61 ± 0.16
  1. 1Data taken from Zamboglou et al., see reference [40] for further information