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Table 5 Multivariate analysis of [68Ga]Ga-DOTA-TOC PET/CT variables with ECOG performance

From: Tumour-to-liver ratio determined by [68Ga]Ga-DOTA-TOC PET/CT as a prognostic factor of lanreotide efficacy for patients with well-differentiated gastroenteropancreatic-neuroendocrine tumours

Variable

Multivariate analysis I

Multivariate analysis II

Multivariate analysis III

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

EGOG performance status (1 vs. 0)

3.518 (0.988–12.525)

0.052

3.528 (1.000–12.454)

0.050

3.188 (0.908–11.191)

0.070

Tumour-to-liver ratio (TLR) (< 8.1 vs. ≥ 8.1)

3.182 (1.189–8.514)

0.021*

NA

NA

NA

NA

SUVmax (< 42.9 vs. ≥ 42.9)

NA

NA

2.493 (0.960–6.475)

0.061

NA

NA

Whole tumour volume (WTV) (≥ 58.9 cm3 vs. < 58.9 cm3)

NA

NA

NA

NA

2.294 (0.917–5.743)

0.076

  1. NA not assessed
  2. *Statistically significant (p < 0.05)