Fig. 1From: Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degradera Representative co-registered axial FES-PET/CT images in vehicle- or SAR439859-treated mice (the red arrow indicates tumor). b Quantitative analysis of FES-PET signal showing a dose-dependent reduction 4 h after a single administration of SAR439859; the data are expressed as SUVmean (mean ± SD)Back to article page