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Fig. 5 | EJNMMI Research

Fig. 5

From: High uptake of 68Ga-PSMA and 18F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes

Fig. 5

Immunofluorescence staining of U87 tumors. Nuclear staining (DAPI) is shown in blue, antibody staining in green, and tumor borders are outlined in white. Strong reactive astrocytosis (GFAP; a) is visible in the peritumoral region with few astrocytes at the tumor border. Specific staining of blood vessels (vWF; b) is detectable, which is similar within tumor tissue and in the peritumoral region. Few activated microglia (CD11b; c) can be observed in the peritumoral region and inside the tumor. PSMA staining using the antibody NBP1-45057 is positive in vessel-like structures in the tumor center (d) but not outside the tumor

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