Fig. 3

Lesion detection in BCR and monitoring of radiation therapy in a 72-year-old patient with Gleason 7 PCa, who underwent primary surgery and salvage radiation therapy. a Cancer recurrence was detected in the right clavicle (PSA 3.8 ng/ml) which was followed by targeted radiation. b 6 months later the clavicle was unremarkable but another recurrence was detected in the lung (PSA 6.8 ng/ml) again followed by precision radiotherapy. c Another 6 months later, no tumor recurrence was detected (PSA 0.56 ng/ml). Note: the apparent focal PSMA-positivity in the liver (c) could not be confirmed in the cross-sectional planes and was not categorized as PSMA-positive