Fig. 5
From: Comparative evaluation of 68Ga-labelled TATEs: the impact of chelators on imaging
Representative maximum-intensity PET/CT projection images of 68Ga-DOTA-TATE (a, b) and 68Ga-NOTA-TATE (c, d) in healthy volunteers 35–45 min after injection. a Female, 46 years old, 51 kg. Maximum intensity projection image after intravenous injection of 68Ga-DOTA-TATE (2.52 mCi) (pituitary, SUVmax = 7.74; spleen, SUVmax = 25.5; liver, SUVmax = 9.4; kidney, SUVmax = 13.9). b Male, 37 years old, 58 kg. Maximum intensity projection image after intravenous injection of 68Ga-DOTA-TATE (2.80 mCi) (pituitary, SUVmax = 4.2; spleen, SUVmax = 16.3; liver, SUVmax = 7.8; kidney, SUVmax = 10.5). c Female, 35 years old, 33 kg. Maximum intensity projection image after intravenous injection of 68Ga-NOTA-TATE (1.86 mCi) (pituitary, SUVmax = 1.9; spleen, SUVmax = 6.8; liver, SUVmax = 1.4; kidney, SUVmax = 12.5). d Male, 57 years old, 83 kg. Maximum intensity projection image after intravenous injection of 68Ga-NOTA-TATE (3.83 mCi) (pituitary, SUVmax = 0.7; spleen, SUVmax = 3.9; liver, SUVmax = 1.3; kidney, SUVmax = 6.2). Compared with 68Ga-DOTA-TATE, 68Ga-NOTA-TATE imaging provides a potential significant advantage in detecting lesions in the liver region due to the distinctively lower liver background