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Table 2 Regional PET-CBF (mL/min/100 g) and SUVr values (mean ± SD)

From: Multimodal analysis using [11C]PiB-PET/MRI for functional evaluation of patients with Alzheimer’s disease

 

CTL right

CTL left

AD right

AD left

PET-CBF

 Frontal

41.6 ± 4.5

39.9 ± 4.0

38.7 ± 8.7

37.7 ± 8.0

 Temporal

39.9 ± 3.0

36.6 ± 3.1

34.5 ± 8.6*

32.2 ± 7.4

 Parietal

44.3 ± 5.8

41.7 ± 4.7

37.8 ± 10.6*

36.3 ± 9.3*

 Occipital

44.0 ± 5.8

42.3 ± 4.7

39.7 ± 10.4

38.4 ± 9.4

 Cerebellum

45.4 ± 5.9

43.9 ± 5.9

42.7 ± 9.4

41.6 ± 8.7

PiB-SUVr

 Frontal

1.02 ± 0.18

1.04 ± 0.19

1.74 ± 0.28

1.77 ± 0.32

 Temporal

1.00 ± 0.12

0.99 ± 0.12

1.54 ± 0.28

1.54 ± 0.27

 Parietal

1.01 ± 0.16

1.03 ± 0.19

1.79 ± 0.30

1.81 ± 0.31

 Occipital

0.99 ± 0.12

1.02 ± 0.12

1.50 ± 0.24

1.51 ± 0.21

  1. CTL healthy control, AD Alzheimer’s disease, PET-CBF cerebral blood flow calculated from early phase PiB-PET data, SUVr standardized uptake value ratio
  2. *P < 0.05
  3. P < 0.00001 compared with the corresponding region of the CTL group