Skip to main content

Table 2 Statistical parametric mapping results for [18F]FDG SUVR and [11C]DPA-713 BPND

From: Coexistence of cerebral hypometabolism and neuroinflammation in the thalamo-limbic-brainstem region in young women with functional somatic syndrome

Anatomical regionBATalairach coordinateCluster sizeVoxel T sizeZ scoreCluster p value
xyzFWEFDRUncorrected
a: [18F]FDG SUVR (FSS group vs. [18F]FDG PET control group)
R uncus3631.7− 1.4− 28.52578.015.43< 0.001< 0.001< 0.001
R hippocampus 31.7− 8.7− 19.7 7.285.14   
R parahippocampus3417.8− 0.8− 15.1 6.764.92   
L thalamus − 9.9− 29.3− 3.63566.704.90< 0.001< 0.001< 0.001
L hippocampus − 33.7− 31.4− 6.81976.935.0< 0.001< 0.001< 0.001
L insula13− 41.6− 31.921.976.804.940.0190.4730.368
L anterior cingulate250− 0.34− 6.71416.754.92< 0.0010.0010.001
L uncus28− 21.82.5− 27.036.164.650.0290.5660.566
b: [11C]DPA-713 BPND (FSS group vs. [11C]DPA713 PET control group)
L thalamus − 4.0− 27.2− 2.0456010.186.41< 0.001< 0.001< 0.001
L amygdala − 25.7− 1.2− 23.52087.785.54< 0.001< 0.001< 0.001
L hippocampus − 25.7− 14.2− 11.1 7.305.34   
L parahippocampus34− 17.8− 6.7− 18.2 5.725.07   
R inferior temporal gyrus2055.4− 13.1− 29.6587.355.36< 0.0010.0340.009
R middle temporal gyrus2055.4− 39.6− 29.6617.225.30< 0.0010.0340.008
R fusiform gyrus2055.4− 34.0− 20.2 6.905.15   
R middle temporal gyrus2149.54.55− 25.51447.115.25< 0.0010.001< 0.001
L superior temporal gyrus38− 37.612.2− 27.5316.795.100.0020.120.047
L fusiform gyrus20− 55.4− 16.6− 21.0226.715.070.0040.1820.087
L superior frontal gyrus6− 5.98.962.2206.494.960.0050.1820.101
L middle frontal gyrus11− 27.734.4− 11.8216.464.950.0050.1820.094
R insula3041.6− 26.219.7126.164.800.0100.3210.196
  1. SUVR standardized uptake value ratio, BPND binding potential, BA Brodmann’s area, L left, R right, FWE family-wise error, FDR false discovery rate