Fig. 3
Maximum intensity projection images of [18F]FDG PET on the baseline (a), after the first cycle of neoadjuvant chemotherapy (b), and after the second cycles of neoadjuvant chemotherapy (c) of an 11-year-old female with osteosarcoma of the right femur. After neoadjuvant chemotherapy, SUVmax has reduced only by 9.7% and 34.0% after 1 cycle and 2 cycles of neoadjuvant chemotherapy, respectively. Although the patient showed a good histologic response to neoadjuvant chemotherapy, pulmonary metastasis developed 16 months after surgery