Changes in cerebral glucose metabolism caused by morphologic features of prodromal idiopathic normal pressure hydrocephalus

EJNMMI Research

Table 1 Demographic data

	NC for PMD (n = 33)	PMD (n = 33)	NC for AVIM (n = 32)	AVIM (n = 32)	NC for iNPH (n = 24)	iNPH (n = 12)
Age, mean (± SD)	72.0 ( ±7.1)	72.0 (± 7.1)	76.0 (± 5.3)	76.0 (± 5.3)	78.8 (± 6.0)	78.8 (± 6.0)
Sex, male/female	27/6	27/6	22/10	22/10	14/10	7/5
Malignancy, presence/absence	30/3	30/3	30/2	30/2	22/2	11/1
Evans index, mean (± SD)	0.271 (± 0.024)	0.315 (± 0.032)	0.276 (± 0.027)	0.339 (± 0.027)	0.277 (± 0.018)	0.349 (± 0.021)
Visual rating scale for TMC 0, dilated/1, normal/2, mildly tight/3, severely tight	2/31/0/0	0/5/9/19	1/30/1/0	0/0/11/21	1/23/0/0	0/0/5/7
Visual rating scale for ESF 0, narrowed/1, normal/2, mildly dilated /3, severely dilated	6/15/11/1	0/14/5/14	1/20/11/0	0/0/14/18	4/16/4/0	0/0/7/5

SD standard deviation, TMC tightness of the medial subarachnoid spaces and with/without tight high convexity sulci, ESF enlarged sylvian fissures, NC normal control, PMD preclinical morphologic features of disproportionately enlarged subarachnoid-space hydrocephalus (DESH), AVIM asymptomatic ventriculomegaly with features of iNPH on magnetic resonance imaging, iNPH idiopathic normal pressure hydrocephalus