Biodistribution and post-therapy dosimetric analysis of [177Lu]Lu-DOTAZOL in patients with osteoblastic metastases: first results

EJNMMI Research

Table 3 Organ absorbed doses (mSv/MBq) of [¹⁷⁷Lu]Lu-DOTA^ZOL

Organs	PT1	PT2	PT3	PT4	Mean	± SD
Adrenals	0.010	0.069	0.016	0.015	0.027	0.028
Brain	0.007	0.061	0.009	0.009	0.021	0.027
Esophagus	0.004	0.060	0.006	0.006	0.019	0.027
Eyes	0.007	0.061	0.009	0.009	0.021	0.027
Gall bladder wall	0.003	0.060	0.005	0.005	0.018	0.028
Left colon	0.005	0.062	0.007	0.007	0.020	0.028
Small intestine	0.004	0.061	0.006	0.006	0.019	0.028
Stomach wall	0.003	0.058	0.004	0.004	0.017	0.027
Right colon	0.003	0.060	0.005	0.005	0.018	0.028
Rectum	0.006	0.062	0.007	0.007	0.021	0.028
Heart wall	0.003	0.059	0.005	0.005	0.018	0.027
Kidneys	0.263	0.555	0.632	0.511	0.490	0.160
Liver	0.003	0.059	0.005	0.005	0.018	0.027
Lungs	0.004	0.059	0.005	0.006	0.019	0.027
Pancreas	0.004	0.061	0.006	0.006	0.019	0.028
Prostate	0.005	0.060	0.006	0.006	0.019	0.027
Salivary glands	0.004	0.060	0.006	0.006	0.019	0.027
Red marrow	0.402	0.551	0.456	0.434	0.461	0.064
Osteogenic cells	2.940	3.770	3.330	3.170	3.300	0.350
Spleen	0.004	0.060	0.006	0.006	0.019	0.027
Testes	0.003	0.057	0.004	0.004	0.017	0.027
Thymus	0.003	0.058	0.004	0.005	0.017	0.027
Thyroid	0.004	0.060	0.006	0.006	0.019	0.027
Urinary bladder wall	0.333	0.364	0.316	0.316	0.332	0.023
Total body	0.069	0.142	0.081	0.077	0.092	0.034