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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Association of metabolic and genetic heterogeneity in head and neck squamous cell carcinoma with prognostic implications: integration of FDG PET and genomic analysis

Fig. 1

Study scheme. A scheme for integrative study of radiogenomics. FDG PET data and genomic mutation data for TCGA-HNSC dataset were obtained from each database of TCIA and TCGA. a The primary tumor was manually assigned, and then ROIs were computed for feature extraction. b MATH calculation using MAF files were done in R. Also, metabolic glycolysis (GlycoS) value was obtained using gene set enrichment analysis. c Clinical data of TCGA-HNSC was gained from TCGA. Total six features were selected and used for radiogenomic analysis. We statistically analyzed radiomic, clinical and genomic data using correlation analysis, Kaplan-Meier analysis, log-rank test

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