Feasibility of radioguided occult lesion localization of clip-marked lymph nodes for tailored axillary treatment in breast cancer patients treated with neoadjuvant systemic therapy

EJNMMI Research

Table 2 Surgery, pathological response, and adjuvant systemic treatment

	n (%)
No. of procedures	38
Breast surgery
Mastectomy	13 (34.2)
Breast-conserving surgery	25 (65.8)
ypT-stage
pCR	7 (18.4)
1	19 (50.0)
2	11 (28.9)
3	1 (2.6)
yiN-stage
yiN0	12 (31.6)
yiN+	26 (68.4)
ypN-stage
0	10 (26.3)
1	18 (47.4)
2	5 (13.2)
3	4 (10.5)
Unknown^a	1 (2.6)
Outcome ROLL-marked node
pCR	10 (26.3)
Marker in node^b	8
No marker present	2
Residual disease	27 (71.1)
Macro-metastasis	24
Micro-metastasis	2
Isolated tumor cells	1
Unknown^a	1 (2.6)
Adjuvant systemic therapy
HT	24 (63.2)
HT + TT	4 (10.5)
HT + CT	1 (2.6)
TT	2 (5.3)
No adjuvant systemic therapy	7 (18.4)

^aNo lymph node was found during the ROLL-node procedure in one patient
^bIn one patient, the ROLL-marked node was initially not found, but removed during a second ROLL-node procedure
HT hormone therapy, TT targeted therapy, CT chemotherapy