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Table 1 Patient and tumor characteristics

From: Feasibility of radioguided occult lesion localization of clip-marked lymph nodes for tailored axillary treatment in breast cancer patients treated with neoadjuvant systemic therapy

 

n (%)

No. of procedures

38

Median age (years)

51 (range 31–83)

cT-stage prior to NST

 Tis

1 (2.6)

 1

4 (10.5)

 2

23 (60.5)

 3

6 (15.8)

 4

4 (10.5)

cN-stage prior to NST

 1

23 (60.5)

 2

9 (23.7)

 3

6 (15.8)

Axillary lymph node stage on pretreatment PET/CT

 cN<4 (< 4 18F-FDG-avid nodes)

26 (68.4)

  1

10

  2

14

  3

2

 cN4+ (≥ 4 18F-FDG-avid nodes)

12 (31.6)

Tumor histology

 Ductal carcinoma in situ

1 (2.6)

 Ductal carcinoma

33 (86.8)

 Lobular carcinoma

3 (7.9)

 Other

1 (2.6)

Receptor status

 HR-positive/HER2-negative

28 (73.7)

 Triple negative

6 (15.8)

 HER2-positive

4 (10.5)

NST regimen

 ddAC

7 (18.4)

 ddAC + paclitaxel

21 (55.3)

 ddAC + CP

3 (7.9)

 CP

2 (5.3)

 PTC-P

3 (7.9)

 Endocrine

2 (5.3)

  1. Tis ductal carcinoma in situ, 18F-FDG [18F]fluorodeoxyglucose, PET/CT positron emission tomography combined with computed tomography, HR hormone receptor, HER2 human epidermal growth factor receptor 2, NST neoadjuvant systemic treatment, ddAC doxorubicine and cyclophosphamide (dose dense), CP carboplatin and paclitaxel, PTC-P paclitaxel, trastuzumab, carboplatin, and pertuzumab