From: PSMA expression level predicts differentiated thyroid cancer aggressiveness and patient outcome
Characteristics | PSMA expression | Overall | ||
---|---|---|---|---|
Negative | Positive | |||
Score 0 (n = 12) | Score 1 (n = 25) | Score 2 (n = 22) | N = 59 | |
Age | ||||
< 55 years | 8 | 12 | 13 | 33 |
≥ 55 years | 4 | 13 | 9 | 26 |
Sex | ||||
 Male | 3 | 6 | 5 | 14 |
 Female | 9 | 19 | 17 | 45 |
Histological DTC subtype | ||||
 Well differentiated | ||||
  Papillary | 12 | 21 | 16 | 49 |
  Follicular | 0 | 2 | 2 | 4 |
 Poorly differentiated | 0 | 2 | 4 | 6 |
Primary tumor site | ||||
 Left lobe | 7 | 8 | 11 | 26 |
 Right lobe | 2 | 13 | 7 | 22 |
 Left lobe + right lobe | 2 | 2 | 4 | 8 |
 Isthmus | 0 | 1 | 0 | 1 |
 Left lobe + isthmus | 0 | 1 | 0 | 1 |
 Right lobe + isthmus | 1 | 0 | 0 | 1 |
TNM | ||||
 T1/T2 | 6 | 17 | 10 | 33 |
 T3/T4 | 6 | 8 | 12 | 26 |
 N0 | 7 | 19 | 12 | 38 |
 N+ | 5 | 6 | 10 | 21 |
 M0 | 12 | 22 | 16 | 50 |
 M+ | 0 | 3 | 6 | 9 |
Stage | ||||
 I/II | 12 | 20 | 15 | 47 |
 III/IV | 0 | 5 | 7 | 12 |
Vascular invasion | Â | |||
 No | 6 | 16 | 7 | 29 |
 Yes | 6 | 9 | 15 | 30 |
Status of surgical margins | ||||
 Free | 9 | 20 | 16 | 45 |
 Involved | 3 | 5 | 6 | 14 |
Recurrence | ||||
 No | 9 | 19 | 12 | 40 |
 Yes | 3 | 6 | 10 | 19 |
Radioiodine refractoriness | ||||
 No | 10 | 21 | 16 | 47 |
 Yes | 2 | 4 | 6 | 12 |
Status at last follow-up | ||||
 No evidence of disease | 10 | 21 | 15 | 46 |
 Recurrence/progressive disease or death | 2 | 4 | 7 | 13 |