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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: In vivo long-lasting alterations of central serotonin transporter activity and associated dopamine synthesis after acute repeated administration of methamphetamine

Fig. 2

The accumulation of 4-[18F]ADAM, showing SERT availability, tended to decrease in most brain regions with increasing METH dose in rats. The higher dose of METH (10 mg/kg) caused a dramatic reduction of SERT availability. The accumulated radioactivity is expressed as a percentage of the injection dose/tissue gram (%ID/g) as the mean ± SD of 6–8 rats per group. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to the control group

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