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Table 5 Radiotherapy for locally advanced salivary gland carcinomas

From: Texture analysis of pretreatment [18F]FDG PET/CT for the prognostic prediction of locally advanced salivary gland carcinoma treated with interstitial brachytherapy

First Author, Year Cancer type No. of patients Treatment LC rates (5-, 10-year) PFS rates 5-year OS rates 5-, 10-year
Mendenhall, 2004 [36] T4 ACC 42 Radiotherapy 44%, 30% / 50%, 29%
Chen, 2006 [37] T4 salivary gland carcinomas 12 Radiotherapy 42%, 30% / 42%, 37%
Douglas, 2000 [38] Locally advanced ACC 151 fast Neutron radiotherapy 57%, / / 72%, /
Gentile, 2017 [29] Nasopharynx ACC involving the skull base 14 Proton beam therapy / / 59%, /
Saitoh, 2017 [39] Inoperable adenocarcinomas 47 Carbon-ion radiotherapy 79.3%, / / 43.4%, /
Jensen, 2015 [40] Inoperable or subtotally resected ACC 58 Intensity-modulated radiotherapy (IMRT) and carbon-ion therapy 59.6%, / 48.4%, / 76.5%, /
Jensen, 2015 [30] 37 Photon therapy 39.9%, / 27%, / 58.7%, /
Inoperable malignant salivary gland tumors 16 Carbon-ion therapy followed by IMRT (3-year) 75, / (3-year) 49.2%, / (3-year) 74.5%, /
Takagi, 2014 [31] Inoperable ACC 56 Proton therapy or carbon-ion therapy alone 66%, / 34%, / 51%, /
  1. ACC adenoid cystic carcinoma, LC local control, PFS progression-free survival, OS overall survival