Texture analysis of pretreatment [18F]FDG PET/CT for the prognostic prediction of locally advanced salivary gland carcinoma treated with interstitial brachytherapy

EJNMMI Research

Table 3 Log-rank tests of clinicopathologic factors, conventional PET parameters, and significant texture features for PFS

Factors or parameters	Number (%)	Value of parameters (mean ± standard deviation)	3-year PFS rates	P value
Tumor site				0.057
Major salivary gland			72.3%
Minor salivary gland			31.5%
N classification				0.122
N0			56.1%
N+			44.4%
M classification				0.217
M0			61.9%
M1			32.6%
Histologic grade				0.855
High grade			33.2%
Low grade			80.0%
Primary or recurrent tumor				0.352
Primary tumor			63.6%
Recurrent tumor			41.5%
SUVmax (g/cm³)				0.455
≤ 2.92	15 (35%)	2.36 ± 0.10	37.1%
> 2.92	28 (65%)	6.27 ± 0.54	67.6%
MTV (cm³)				0.496
≤ 57.27	33 (77%)	22.46 ± 2.45	59.6%
> 57.27	10 (23%)	101.52 ± 9.09	34.3%
TLG (g)				0.246
≤ 37.95	14 (33%)	21.39 ± 2.54	50.2%
> 37.95	29 (67%)	133.61 ± 18.09	56.7%
Minimum intensity				0.019*
≤ 4403	30 (70%)	2813.37 ± 178.48	57.5%
> 4403	13 (30%)	6017.31 ± 414.55	0
Mean intensity				0.027*
≤ 6328	25 (58%)	4015.43 ± 258.37	61.1%
> 6328	18 (42%)	9426.24 ± 639.15	23.7%
Median intensity				0.027*
≤ 6119	26 (60%)	3815.35 ± 254.19	61.1%
> 6119	17 (40%)	8942.24 ± 598.51	23.7%
Root mean square				0.027*
≤ 6431	26 (60%)	4119.35 ± 262.72	61.1%
> 6431	17 (40%)	9752.68 ± 681.31	23.7%
Long run emphasis				0.012*
≤ 3.79	34 (79%)	2.17 ± 0.13	0
> 3.79	9 (21%)	5.96 ± 0.93	66.3%

PET positron emission tomography, PFS progression-free survival, SUVmax maximum standardized uptake value, MTV metabolic tumor volume, TLG total lesion glycolysis, "*" represents P<0.05