Table 3 Biodistribution of [¹²⁵I]CPCR4.3 in Black Six normal mice at 60 min p.i. (groups of n = 4). To determine CXCR4 specificity of tracer uptake, 50 μg AMD3100 (2 mg/kg) were coinjected. Data are cited as %iD/g and are means ± SD

0.39 ± 0.05

0.32 ± 0.11

0.36 ± 0.10

0.34 ± 0.10

21.18 ± 2.92

23.74 ± 4.68

4.63 ± 2.94

1.08 ± 0.59

1.14 ± 0.87

0.42 ± 0.21

30.36 ± 2.09

35.67 ± 2.48

4.07 ± 0.25

4.70 ± 1.11

1.65 ± 0.25

0.49 ± 0.07*

8.03 ± 2.91

2.78 ± 1.72*

1.43 ± 0.37

0.33 ± 0.14*

0.13 ± 0.11

0.07 ± 0.05