Fig. 7
Whole body PET images in representative nude mice with MDA-MB-231 tumor from three groups tested. Coronal PET images obtained after 60-min post-injection of 68Ga-DOTA-Ahx-BN peptide (~ 100 ng, ~ 100 μCi). (Left) Tumor is clearly visible in the image suggesting receptor-specific tumor uptake. (Right) Tumor is hardly detectable in PET image under blocking condition in the presence of 300 μg cold BN peptide to block BN/GRP receptors. Arrows indicate the location of tumors