Skip to main content

Advertisement

Table 3 Planned and delivered dose results based on normalized 99mTc-MAA SPECT and 90Y-microsphere PET respectively

From: Analysis of differences between 99mTc-MAA SPECT- and 90Y-microsphere PET-based dosimetry for hepatocellular carcinoma selective internal radiation therapy

  Normalized 99mTc-MAA SPECT
Mean ± SD
90Y-MS PET
Mean ± SD
Bias [95% CI] Pearson’s correlation
DT (Gy) 169 ± 40 165 ± 47 4 [−5; 13] 0.87 (P = 3.10−8)
D20 (Gy) 250 ± 67 251 ± 78 − 1 [− 15; 14] 0.89 (P = 7.10−9)
D50 (Gy) 156 ± 44 144 ± 51 12 [0; 25] 0.79 (P = 4.10−6)
D70 (Gy) 104 ± 36 91 ± 38 13 [1; 25]* 0.67 (P = 3.10−4)
V205 (%) 30 ± 18 30 ± 16 0 [− 3; 4] 0.85 (P = 1.10−7)
DNL (Gy) 36 ± 16 34 ± 15 1 [− 1; 4] 0.91 (P = 6.10−10)
  1. MS microsphere, MAA macroaggregated albumin, SD standard deviation, DT mean dose to the tumor, D20 minimum dose to 20% of the tumor volume, D50 minimum dose to 50% of the tumor volume, D70 minimum dose to 70% of the tumor volume, V205 percentage of the volume receiving more than 205 Gy, DNL mean dose to the normal liver. Bias and correlation are with respect to 90Y-MS PET
  2. *P ≤ 0.05