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Table 1 Organ absorbed doses and contributions to effective doses for 11C-Cimbi-36 and 11C-Cimbi-36_5

From: Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

 

Absorbed dose

(μGy/MBq)

Contributions to effective dose

(μSv/MBq)

Target organ

11C-Cimbi-36

11C-Cimbi-36_5

11C-Cimbi-36

11C-Cimbi-36_5

Adrenals

5.83

5.52

0.05

0.05

Brain

6.12

6.72

0.06

0.07

Breasts

2.38

2.42

0.29

0.29

Esophagus

3.54

3.50

0.14

0.14

Eyes

2.19

2.32

0.00

0.00

Gallbladder wall

5.85

4.88

0.05

0.05

Left colon

5.24

5.70

0.25

0.28

Small intestine

5.55

4.91

0.05

0.05

Stomach wall

5.46

7.56

0.66

0.91

Right colon

3.23

3.15

0.16

0.15

Rectum

2.99

2.57

0.07

0.06

Heart wall

10.70

9.84

0.10

0.09

Kidneys

11.80

10.50

0.11

0.10

Liver

15.70

13.20

0.63

0.53

Lungs

8.61

8.31

1.03

1.00

Ovaries

3.14

2.91

0.13

0.12

Pancreas

13.30

11.60

0.12

0.11

Prostate

2.67

2.29

0.01

0.01

Salivary glands

2.36

2.48

0.02

0.02

Red marrow

4.19

4.33

0.50

0.52

Osteogenic cells

3.37

3.72

0.03

0.04

Spleen

18.40

17.90

0.17

0.17

Testes

1.89

1.87

0.08

0.07

Thymus

3.20

3.21

0.03

0.03

Thyroid

6.37

6.52

0.26

0.26

Urinary bladder wall

12.40

2.40

0.50

0.10

Uterus

3.51

2.85

0.02

0.01

Effective dose

  

5.5

5.3