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Fig. 4 | EJNMMI Research

Fig. 4

From: Biodistribution and radiation dosimetry of the novel hypoxia PET probe [18F]DiFA and comparison with [18F]FMISO

Fig. 4

Time-activity curves in representative organs. [18F]DiFA was rapidly cleared from the organs. The accumulation in the gallbladder peaked after 4 h, since [18F]DiFA that was excreted in the bile due to hepatobiliary excretion stayed in the gallbladder and was secreted with a meal (at 4 h after examination). The accumulation in the brain slowly increased, reflecting the improvement in water solubility, and after 4 h, it peaked and then decreased. The data are the mean ± SD of results from six volunteers

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