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Table 3 Absorbed organ dose (mGy/MBq) and effective dose (mSv/MBq) after injection of [18F]-PSS232. Coefficients of variation (COV) (ratio of SD to mean)

From: Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

Organ

Mean

COV

Minimum

Maximum

Adrenals

0.0138

2.2

0.0134

0.0143

Brain

0.0107

10.3

0.0089

0.0121

Breasts

0.0064

17.2

0.0050

0.0080

Gallbladder wall

0.2295

55.4

0.0567

0.4340

Lower large intestine wall

0.0130

7.7

0.0115

0.0145

Small intestine

0.0643

14.6

0.0510

0.0816

Stomach wall

0.0118

5.1

0.0111

0.0128

Upper large intestine wall

0.0217

6

0.0207

0.0246

Heart wall

0.0153

9.2

0.0129

0.0172

Kidneys

0.0209

11

0.0177

0.0249

Liver

0.0547

18.1

0.0440

0.0727

Lungs

0.0090

7.8

0.0081

0.0101

Muscle

0.0108

8.3

0.0093

0.0119

Ovaries

0.0156

6.4

0.0138

0.0169

Pancreas

0.0197

12.2

0.0175

0.0246

Red marrow

0.0140

4.3

0.0129

0.0145

Osteogenic cells

0.0136

11.8

0.0113

0.0154

Skin

0.0059

13.6

0.0048

0.0071

Spleen

0.0105

14.3

0.0092

0.0135

Testes

0.0071

14.1

0.0054

0.0088

Thymus

0.0121

10.7

0.0104

0.0147

Thyroid

0.0088

6.8

0.0077

0.0096

Urinary bladder wall

0.0188

43.1

0.0140

0.0368

Uterus

0.0151

4.6

0.0142

0.0164

Total body

0.0123

0.8

0.0121

0.0123

Effective dose

0.0153

3.3

0.0148

0.0163