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Table 1 Histological characteristics and findings at immunohistochemistry evaluating amino acid transporter expression of 40 tumor foci in 25 patients with localized prostate cancer. Note that no tumors were assigned in Gleason grade group 4

From: Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer

Gleason grade/Gleason grade group Number Percent
3 + 3/1 9 22.5
3 + 4/2 11 27.5
4 + 3/3 10 25.0
4 + 5/5 8 20
5 + 4/5 2 5
ASCT2 staining intensity
 Low (1) 4 10
 Moderate (2) 24 60
 High (3) 12 30
LAT1 staining intensity
 Negative (0) 5 12
 Low (1) 25 63
 Moderate (2) 10 25