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Fig. 2 | EJNMMI Research

Fig. 2

From: Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC

Fig. 2

Displacement of [125I-Tyr25]LTT-SS28 from hSST2 binding sites in HEK293-hSST2 cell membranes by increasing concentrations of the following: square, [natGa]Ga-DATA-TOC (IC50 = 1.03 ± 0.08 nM, n = 3); diamond, [natGa]Ga-DOTA-TOC (IC50 = 0.21 ± 0.01 nM, n = 2); and control: asterisk, LTT-SS28 (IC50 = 0.05 ± 0.01 nM, n = 3). Results represent the average IC50 values ± sd of independent experiments performed in triplicate

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