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Table 3 Biodistribution for nano-carrier 188Re-liposome in normal organs of patients (n = 12)

From: A phase 0 study of the pharmacokinetics, biodistribution, and dosimetry of 188Re-liposome in patients with metastatic tumors

Normal organ Time point
(%ID/kg) 1 h 8 h 24 h 48 h 72 h
Lungs 9.4 ± 2.3 7.5 ± 2.7 6.8 ± 2.6 3.7 ± 2.2 2.2 ± 1.4
Liver 14.7 ± 5.4 12.6 ± 4.9 11.2 ± 4.7 8.7 ± 4.4 5.9 ± 4.5
Heart contents 4.2 ± 1.9 3.1 ± 1.8 2.7 ± 1.4 1.4 ± 1.1 0.7 ± 0.5
Spleen 13.2 ± 8.0 12.3 ± 8.3 11.4 ± 7.3 9.0 ± 7.0 6.3 ± 6.3
Kidneys 8.1 ± 5.8 6.1 ± 2.5 5.7 ± 2.5 3.7 ± 1.5 2.1 ± 2.0
Muscle 0.4 ± 0.3 0.2 ± 0.3 0.1 ± 0.2 0.1 ± 0.1 0.1 ± 0.1
  1. Data is expressed as a percentage of injected activity per kilogram (%ID/kg) ± SD