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Table 2 Pharmacokinetic parameters for nano-carrier 188Re-liposome uptake after intravenous injection for patients (n = 12) with tumors

From: A phase 0 study of the pharmacokinetics, biodistribution, and dosimetry of 188Re-liposome in patients with metastatic tumors

Parameters Blood Plasma
Cmax (%ID/mL) 0.01 ± 0.01 0.02 ± 0.02
Cl (mL/h) 749.40 ± 663.19 494.26 ± 447.01
AUC0→∞(%ID /mL*h) 0.33 ± 0.32 0.50 ± 0.46
T1/2Z (h) 36.73 ± 14.00 52.02 ± 45.21
  1. Pharmacokinetic parameters are determined using WinNonlin software version 5.3 (Pharsight Corp., Mountain View, CA, USA)
  2. Cmax maximum concentration, Cl clearance rate, AUC area under curve, T1/2Z elimination half-life