Fig. 1

Box plots of TBRpeak by the results of visual evaluation of [¹⁸F]FMISO PET/CT (a), TBRpeak of operable and inoperable patients (c), TBRpeak by HIF-1α immunohistochemical expressions evaluated by 4 categories (0, 1, 2, and 3) (d), and 2 categories (low and high) (e). Red horizontal dot lines indicate TBRpeak = 1.24 calculated by the receiver operating characteristic analysis (b). Lines on whiskers and boxes in box blots indicate maximum, upper quartile, median, lower quartile, and minimum, respectively