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Table 2 Pharmacokinetic parameters for simulating TACs using SRTM

From: Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies

 

[18F]flutemetamol

[18F]florbetaben

Level

BPND

BPND

BPND I

0.020

0.021

BPND II

0.208

0.277

BPND III

0.397

0.532

BPND IV

0.585

0.787

BPND V

0.774

1.042

  1. BPND binding potential of target tissue, [18F]flutemetamol: R1 = 0.775, k2 = 0.02, [18F]florbetaben: R1 = 0.904, k2 = 0.03