Skip to main content

Table 1 Findings by CT, PET, necropsy, and microbiology of the individual pigs. Fifty-five of the OM lesions were found in the right hind limb, and one was found in right humerus

From: An untapped potential for imaging of peripheral osteomyelitis in paediatrics using [18F]FDG PET/CT —the inference from a juvenile porcine model

Piga Number of OM (CT) Number of OM (PET) Number of OM (necropsy and/or histology) Microbial S. aureus Vol. ranges cm3 SUV ranges g/ml FDG activity MBq/kg
1a 4 4 3 Yes 0.16–2.54 2.6–4.4 7.48
2a 1 1 1 Yesc 2.05 3.9 9.73
3a 2 2 1 Yesc 0.02–0.23 5.2–5.7 9.36
4a 1 1 1 Yes 3.76 2.4 18.86
5a 3 3 3 Yesc 0.42–2.41 4.0–7.3 18.86
6 5 5 5 Yes 0.07–0.36 2.3–5.9 17.09
7a 4 4 4 Yes 0.17–0.73 2.9–4.5 22.09
8a 5 5 6b Yesc 0.33–0.59 10.5–16.3 22.42
9a 2 2 1 Yesc 0.01–0.29 3.4–9.0 6.10
10 3 3 1 Yesc 0.01–4.18 4.0–9.2 6,67
11 4 4 3 Yesc 0.07–0.36 3.0–6.4 6.23
12 3 3 2 Yesc 0.21–1.52 2.4–8.0 5.97
13 2 2 1 Yes 0.29–0.79 4.6–5.9 5.0
14 4 4 4 Yesc 0.25–0.45 4.4–5.1 3.98
15 3 3 3 Yes 0.09–0.36 3.0–6.1 5.18
16 3 3 3 Yes 0.03–1.37 1.0–3.9 5.55
17 1 1 1 Yesc 0.03 6.1 5.42
18 2 2 2 Yesc 0.58–2.28 7.8–10.1 5.0
19 3 3 3 Yesc 0.05–3.84 4.0–7.8 5.85
20 1 1 2b Yesc 0.01 3.6 4.86
  1. aSome data from these pigs have been published previously: pigs 1–3 [14, 15], pigs 5–8 [16], and pigs 1–9 [40, 41]
  2. bPigs 8 and 20 were diagnosed with osteomyelitis by necropsy and/or histology disclosing affection of the proximal and intermediary phalanges of toe no. IV in pig 8 and the intermediary and distal phalanges of toe no. V in pig 20; by scanning, only one of the lesions in each of the pigs was identified
  3. cS. aureus identified by cultivation from a periosseous abscess (pigs 2, 3, 9–12, 14, 17–18), from an arthritic lesion (pig 8), from an inoculation site abscess (pig 19), and by immunohistochemistry (pigs 5 and 20)