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Table 4 Change in body weight of nude mice after different treatment conditions

From: Intratumoral 18F-FLT infusion in metabolic targeted radiotherapy

Treatment

Before Treatment (g)

10 Days after treatment (g)

Days to reach 5Td (g)

Control

27.0 ± 0.7

26.2 ± 2.4

29.9 ± 2.2

i.t. FLT

26.5 ± 1.5

27.2 ± 1.3

30.4 ± 1.6

i.t. 18F-FLT 15 MBq

30.0 ± 1.1

28.4 ± 0.5

32.7 ± 1.1

i.t. 18F-FLT 25 MBq

27.3 ± 2.2

26.7 ± 0.9

28.9 ± 2.2

15 Gy EBRT

25.8 ± 2.8

26.4 ± 0.5

27.9 ± 2.4

i.t. 5FU

26.5 ± 2.9

26.0 ± 2.8

29.5 ± 4.3

i.t. 5FU + 15 Gy EBRT

23.8 ± 3.4

25.6 ± 0.6

28.1 ± 1.2

i.t. 5FU + i.t. 18F-FLT 15 MBq

23.1 ± 0.3

23.6 ± 0.4

24.8 ± 1.0

i.t. 18F-FDG 15 MBq

27.3 ± 1.9

28.1 ± 1.6

29.9 ± 2.9

i.t. 5FU + i.t. 18F-FDG 15 MBq

30.6 ± 0.8

30.0 ± 1.7

32.3 ± 1.0

i.v. 18F-FLT 10 MBq

26.8 ± 1.9

27.6 ± 0.5

29.3 ± 0.6

  1. Three to five animals were included in each group