From: Intratumoral 18F-FLT infusion in metabolic targeted radiotherapy
Treatment | Before Treatment (g) | 10 Days after treatment (g) | Days to reach 5Td (g) |
---|---|---|---|
Control | 27.0 ± 0.7 | 26.2 ± 2.4 | 29.9 ± 2.2 |
i.t. FLT | 26.5 ± 1.5 | 27.2 ± 1.3 | 30.4 ± 1.6 |
i.t. 18F-FLT 15 MBq | 30.0 ± 1.1 | 28.4 ± 0.5 | 32.7 ± 1.1 |
i.t. 18F-FLT 25 MBq | 27.3 ± 2.2 | 26.7 ± 0.9 | 28.9 ± 2.2 |
15 Gy EBRT | 25.8 ± 2.8 | 26.4 ± 0.5 | 27.9 ± 2.4 |
i.t. 5FU | 26.5 ± 2.9 | 26.0 ± 2.8 | 29.5 ± 4.3 |
i.t. 5FU + 15 Gy EBRT | 23.8 ± 3.4 | 25.6 ± 0.6 | 28.1 ± 1.2 |
i.t. 5FU + i.t. 18F-FLT 15 MBq | 23.1 ± 0.3 | 23.6 ± 0.4 | 24.8 ± 1.0 |
i.t. 18F-FDG 15 MBq | 27.3 ± 1.9 | 28.1 ± 1.6 | 29.9 ± 2.9 |
i.t. 5FU + i.t. 18F-FDG 15 MBq | 30.6 ± 0.8 | 30.0 ± 1.7 | 32.3 ± 1.0 |
i.v. 18F-FLT 10 MBq | 26.8 ± 1.9 | 27.6 ± 0.5 | 29.3 ± 0.6 |