Multi-modal image analysis for semi-automatic segmentation of the total liver and liver arterial perfusion territories for radioembolization

Jafargholi Rangraz, Esmaeel; Coudyzer, Walter; Maleux, Geert; Baete, Kristof; Deroose, Christophe M.; Nuyts, Johan

doi:10.1186/s13550-019-0485-x

EJNMMI Research

Table 4 Patient characteristics

From: Multi-modal image analysis for semi-automatic segmentation of the total liver and liver arterial perfusion territories for radioembolization

Characteristics	All cases	Training set	Test set
Patient information
Sex (female/male)	6/11	3/4	3/7
Age in years, median [range]	60.5 [32.9, 72.3]	60.6 [32.9, 72.3]	58.2 [36.2, 69.5]
Height in meter, median [range]	175 [160, 193]	174 [163, 186]	178 [160, 193]
Weight in kg, median [range]	81 [61, 123]	79 [71, 100]	84 [61,123]
Tumor cell type, n (%)
Colorectal cancer	7 (41%)	1 (14%)	6 (60%)
Breast cancer	2 (12%)	2 (29%)	0 (0%)
Melanoma cancer	2 (12%)	2 (29%)	0 (0%)
Esophageal cancer	2 (12%)	1 (14%)	1 (10%)
HCC	1 (6%)	1 (14%)	0 (0%)
Neuroendocrine tumor	1 (6%)	0 (0%)	1 (10%)
Colon cancer	1 (6%)	0 (0%)	1 (10%)
Cholangiocellular	1 (6%)	0 (0%)	1 (10%)
Volumes from prescription sheet (cc), median [range]
Total liver (WL)	1892 [1268, 3127]	1878 [1663, 2721]	1907 [1268, 3127]
Total liver (L-LPT)	448 [215, 1197]	390 [251, 1050]	514 [215, 1197]
Total liver (R-LPT)	1496 [677, 1930]	1330 [1223, 1839]	1533 [677, 1930]
Healthy liver (WL)	1700 [1218, 2988]	1700 [1513, 2528]	1694 [1218, 2988]
Healthy liver (L-LPT)	390 [135, 1115]	390 [201, 1041]	395 [135, 1115]
Healthy liver (R-LPT)	1319 [700, 1873]	1241 [1184, 1612]	1344 [700, 1873]
Tumor (WL)	150 [7, 643]	150 [28, 494]	153 [7, 643]
Tumor (L-LPT)	36 [0, 312]	18 [0, 109]	51 [0, 312]
Tumor (R-LPT)	130 [7, 479]	146 [10, 479]	93 [7, 331]
Clinical information from prescription sheet (%), median [range]
Tumor involvement (WL)	7.1 [0.4, 27.8]	8.5 [1.5, 24.2]	5.7 [0.4, 27.8]
Tumor involvement (L-LPT)	6.9 [0.0, 47.3]	4.8 [0.0, 28.7]	8.7 [0.0, 47.3]
Tumor involvement (R-LPT)	8.6 [0.8, 27.7]	11.0 [0.8, 27.7]	6.5 [1.1, 20.0]
L-LPT to WL volume	25 [11, 60]	23 [12, 39]	27 [11, 60]
Lung shunt fraction (LSF)	6.4 [3.8, 8.5]	7.4 [3.8, 8.2]	5.8 [3.9, 8.5]
Day differences between different studies and SIRT (days), median [range]
¹⁸F-FDG and SIRT	20 [3, 58]	35 [3, 58]	16 [6, 40]
^99mTc-MAA and SIRT	21 [15, 41]	21 [15, 32]	21 [15, 41]
Prescription
IA calculation method
BSA method, n (%)	14 (82%)	7 (100%)	7 (70%)
Partition model, n (%)	3 (18%)	0 (0%)	3 (30%)
IA in GBq, median [range]
WL	1.850 [1.268, 2.502]	1.837 [1.746, 2.063]	1.882 [1.268, 2.502]
L-LPT	0.457 [0.228, 1.089]	0.457 [0.228, 0.724]	0.469 [0.248, 1.089]
R-LPT	1.339 [0.733, 1.783]	1.339 [1.113, 1.640]	1.414 [1.113, 1.640]

WL whole liver
L-LPT left liver perfusion territory
R-LPT right liver perfusion territory

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