Fig. 1From: Partial-volume correction in dynamic PET-CT: effect on tumor kinetic parameter estimation and validation of simplified metricsTime-activity curves of relative change in activity concentrations (AC) after PVC using several HYPR settings. Frames of 0–4 min (a) and 4–60 min (b) post-injection. Results of a typical mediastinal lymph node metastasis are shown. Note the temporality of PVE with a spill in at early timeframes. Corresponding original PET images (c) with the lesion volume-of-interest in red demonstrate blood pool activity near the VOI and increasing tumor-to-background contrast over timeBack to article page