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Fig. 5 | EJNMMI Research

Fig. 5

From: First-in-class positron emission tomography tracer for the glucagon receptor

Fig. 5

Hepatic binding of [68Ga]Ga-DO3A-S01-GCG and [68Ga]Ga-DO3A-S02-GCG can be competed away. [68Ga]Ga-DO3A-S01-GCG binding in the liver, spleen, and bone marrow, but not other tissues, could be competed away by co-injection with 1 mg/kg precursor peptide (a). Similarly, [68Ga]Ga-DO3A-S02-GCG binding in the liver and spleen could be competed away by 1 mg/kg precursor peptide (b), but to a lesser extent than for [68Ga]Ga-DO3A-S01-GCG (c). Each bar represents the average of n = 4 animals

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