Variable | Derivation (N = 340) | Validation (N = 138) | p value |
---|---|---|---|
Scar, n (%) | 105 (31%) | 40 (29%) | 0.68 |
Demographics | |||
Age | 67.3 (12.3) | 68.3 (12.0) | 0.40 |
Male gender, n (%) | 232 (68%) | 98 (71%) | 0.55 |
Caucasian, n (%) | 310 (91%) | 126 (91%) | 0.96 |
Past medical history | |||
Coronary artery disease, n (%) | 161 (47%) | 64 (46%) | 0.85 |
STEMI/NSTEMI, n (%) | 50 (15%) | 18 (13%) | 0.64 |
Prior PCI, n (%) | 96 (28%) | 32 (23%) | 0.26 |
Prior CABG, n (%) | 42 (12%) | 19 (14%) | 0.67 |
HFrEF, n (%) | 51 (15%) | 23 (17%) | 0.65 |
HFpEF, n (%) | 7 (2%) | 5 (4%) | 0.32 |
ICD, n (%) | 10 (3%) | 1 (1%) | 0.14 |
CRT, n (%) | 1 (0%) | 0 (0%) | 0.52 |
Pacemaker, n (%) | 12 (4%) | 4 (3%) | 0.73 |
Hypertension, n (%) | 215 (63%) | 86 (62%) | 0.85 |
Hyperlipidemia, n (%) | 236 (69%) | 86 (62%) | 0.13 |
Smoking, n (%) | 167 (48%) | 57 (42%) | 0.33 |
OSA, n (%) | 65 (19%) | 34 (25%) | 0.18 |
COPD, n (%) | 21 (6%) | 6 (4%) | 0.43 |
Diabetes, insulin dependent, n (%) | 27 (8%) | 7 (5%) | 0.27 |
Dialysis, n (%) | 6 (2%) | 1 (1%) | 0.39 |
Peripheral vascular disease | 41 (12%) | 16 (12%) | 0.89 |
Atrial fibrillation/atrial flutter, n (%) | 57 (17%) | 33 (24%) | 0.07 |
Ventricular tachycardia, n (%) | 6 (2%) | 4 (3%) | 0.43 |
Family history of premature CAD, n (%) | 46 (14%) | 14 (10%) | 0.31 |
Valve disease (moderate or greater), n (%) | 28 (14%) | 10 (11%) | 0.50 |
Medications | |||
Aspirin, n (%) | 211 (62%) | 96 (70%) | 0.12 |
Beta-blocker, n (%) | 187 (55%) | 75 (54%) | 0.90 |
Ticagreloror/plavix/prasugrel, n (%) | 53 (16%) | 21 (15%) | 0.92 |
Statin, n (%) | 222 (65%) | 84 (61%) | 0.36 |
CCB, n (%) | 60 (18%) | 28 (20%) | 0.50 |
Diuretic, n (%) | 105 (31%) | 46 (33%) | 0.60 |
ECG/imaging | |||
ECG Q wave, n (%) | 17 (5%) | 4 (3%) | 0.31 |
ECG ST depression, n (%) | 19 (6%) | 6 (4%) | 0.58 |
ECG paced, n (%) | 19 (6%) | 9 (7%) | 0.69 |
ECG LBBB, n (%) | 18 (5%) | 13 (9%) | 0.09 |
ECG atrial fibrillation/atrial flutter, n (%) | 31 (9%) | 20 (14%) | 0.08 |
Nuclear EF | 59.6 (11.9) | 60.4 (12.4) | 0.53 |
QPS SRS, median (Q1, Q3) | 0.5 (0.0, 3.0) | 0.0 (0.0, 2.0) | 0.20 |
Clinical Presentation | |||
Typical symptoms, n (%) | 28 (8%) | 13 (10%) | 0.62 |