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Fig. 4 | EJNMMI Research

Fig. 4

From: Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques

Fig. 4

Photomicrographs of MR (green) and CD68 (red) immunofluorescence staining. Overlapping domains of expression (MR + CD68) are shown in yellow. DAPI stained nuclei are shown in blue. Some CD68+ macrophages mainly located in the fibrous cap and in the shoulder regions of the atherosclerotic lesions showed MR expression (a). The adventitia underlying atherosclerotic plaques showed more MR expression compared to the adventitia in plaque-free areas of aortas isolated from ApoE-KO and control mice (b)

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