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Table 2 Parameters of CT, FDG PET/CT, and 4DST PET/CT

From: 18F-FDG and 11C-4DST PET/CT for evaluating response to platinum-based doublet chemotherapy in advanced non-small cell lung cancer: a prospective study

Modality

Parameter

Baseline (n = 22)

Baseline (n = 18)

Interim CT or PET (n = 18)

p value

CT

Sum of uni-dimensional measurements of target lesion (cm)

71.9 ± 33.7

71.5 ± 28.7

61.5 ± 28.7

0.24

FDG

Highest SUVmax

12.8 ± 5.0

13.7 ± 5.0

11.1 ± 7.0

0.36

Sum of SUVmax

35.2 ± 33.4

40.5 ± 34.8

29.0 ± 29.9

0.29

MTV

101.6 ± 106.3

115.0 ± 112.5

77.7 ± 87.6

0.35

TLG

618.1 ± 787.8

717.7 ± 838.4

408.1 ± 517.9

0.26

SUL

8.9 ± 4.3

9.5 ± 4.4

7.5 ± 4.4

0.14

Mean SUL of liver

1.8 ± 0.3

1.8 ± 0.3

2.0 ± 0.3

0.38

SD of mean SUL of liver

0.2 ± 0.05

0.2 ± 0.05

0.2 ± 0.03

0.16

4DST

Highest SUVmax

6.6 ± 2.6

6.1 ± 2.6

6.0 ± 2.7

0.73

Sum of SUVmax

19.6 ± 16.6

20.9 ± 17.8

19.7 ± 20.0

0.38

MTV

145.9 ± 268.5

161.9 ± 286.3

80.6 ± 86.1

0.33

TLP

507.6 ± 1107.3

553.9 ± 1187.1

232.6 ± 235.5

0.42

  1. MTV metabolic tumor volume, TLG total lesion glycolysis, SUL lean body mass, TLP total lesion proliferation